Dilawer

An Admixture Calculator for Eurasians

Genealogical testing companies use highly admixed references In other posts, I have mentioned the problems with ancestry proportion tests from genealogical testing companies such as 23andMe, AncestryDNA, and FTDNA, and how useless the test results can be for describing the population history and admixture for individuals from various parts of Eurasia. For example, what does …

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A detailed look at East & North Eurasian Gene Flow to South & West Asians

Here I perform a detailed analysis of East and North Eurasian gene flow to South, South-Central, and West Asians by doing a one-to-one comparison of genomes sampled at about 404,000 Single Nucleotide Polymorphism (SNP) positions, using the program BEAGLE. To do this I utilize many genomes from northern and eastern Asia publicly available from the …

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Characterising private and shared signatures of positive selection in 37 Asian populations

A new paper by Liu et al1 examines patterns of genetic diversity and positive natural selection, and finds that populations predominantly located in South Asia underwent considerably different adaptation as compared with populations from the other geographical regions. Here is their abstract: “The Asian Diversity Project (ADP) assembled 37 cosmopolitan and ethnic minority populations in …

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23andMe’s New Admixture Date Estimator

I received a couple of inquiries asking what my thoughts were on the recently introduced 23andMe “Admixture Date Estimator”, which is detailed in their White Paper no. 23-14. Their theory appears mathematically and statistically sound, and appears to be heavily based on the size and distribution of the segments in your genome, however, the model …

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